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WHITE PAPERS AND CASE STUDIES

• Use Of Maurice CE-SDS In ICH Q6B-Based Biosimilar Comparability Exercises

  The route to market for biosimilars places strong emphasis on the analytical and characterization techniques used to investigate the structure of the molecule and, importantly, side-by-side comparability. 

• Service Managers’ Buyer’s Guide

  The past few decades have fundamentally redefined the boundaries, perception, and expectations of what service delivery means for the modern economy. The days of localized, disparate support have in many instances been superseded by a coherent, connected strategy, and even within those small support offerings, the options and expectations for how service would be scheduled, how parts would be allocated, and how service itself is delivered has only grown more complex.

• Industrial Smart Components: What To Use When

  The objective of this paper is to provide an overview of the current standard industrial HID Global RFID tag portfolio and provide a guideline of the RFID tag family’s main propositions.

• Advanced Control Technology For Laser Material Processing

  Simple, fast, accurate, and flexible control in laser materials processing; how to make it easier for system integrators to design and build advanced systems for a new age of laser applications.

• Baluns Basics Primer: A Tutorial on Baluns, Balun Transformers, Magic-Ts, and 180° Hybrids

  Baluns have long been ubiquitous in low frequency audio, video, and antenna driving applications. The need for high speed, low noise data transfer has driven the advancement of the balun to higher frequencies and superior performance. 

• Isolator Vs. Optocoupler Technology

  While optocouplers have been the dominant signal isolation solution for a long time, a new breed of higher-performance CMOS isolator solutions will ultimately out-mode the venerable optocoupler.

• Brand Spirits Leader Digitizes Business Operations With The SIMATIC IT Suite

  Gruppo Campari closed 26 acquisitions in the spirits industry in the past two decades to become the world’s sixth player, with over 50 premium and super-premium brands. With each acquisition, Gruppo Campari needs to integrate new products, plants and assets into its operations management systems. By 2012 they realized there was no standard workflow for document authoring and validation, and information was shared via email or phone. Using Siemens technology, Gruppo Campari has created a unified repository for all product specifications and increased the efficiency of product development and manufacturing processes.

• Full IND Program: Exceeding Requirements For Submission

  Follow a compound through a full cycle of IND development, from modifications to the synthetic route to formulation development and API manufacturing.

• Targeting Once Inaccessible Phospho-Proteins With RePlex

  Vividion Therapeutics is a small molecule company harnessing its expertise in target biology, chemistry, and mass spectrometry to transform the future of human health. They were frustrated with their process when monitoring quantitative phospho-protein changes as it was notoriously problematic and slow. By transferring their assays over to Simple Western™ with Jess™ combined with Jess’ RePlex™ module they are able to increase throughput and improve the accuracy of his phospho-protein quantification.

• Eliminating USP <88> In Vivo Animal Bioreactivity Testing For Polymer Characterization

  There has been growing awareness about the environmental and ethical implications of plastics used in bioprocessing. The time for a shift to well-studied, proven in vitro cytotoxicity testing is now.

• Automatic Score-Based Treatment Path For Site Users

  A biopharmaceutical company had a Phase II study with 300 patients in 5 countries. At a key point in the study each patient’s treatment path depended on a score calculated from data collected over the previous period. Cmed was able to provide them with a solution that would enforce a workflow to ensure the accuracy of the data used in the score calculation.

• Gwinnett County Explores Benefits Of Digital Twins At Pump Station

  As a leader in the water industry, Gwinnett County Department of Water Resources (GCDWR) aims to provide superior water services at an excellent value. The multi-award-winning utility has been recognized both statewide and nationally for excellence in water production, wastewater treatment, infrastructure development, and customer satisfaction. GCDWR operates and maintains two water production facilities; three water reclamation facilities; more than 200 pump stations; and nearly 8,000 miles of water, sewer, and stormwater pipes that provide essential services to more than 900,000 people each day.