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WHITE PAPERS AND CASE STUDIES

• Impact Of Glycosylation On The Effector Functions Of Monoclonal Antibodies

  In an example using rituximab and its biosimilars, explore the significance of minor differences of glycosylation in antibodies and its impact on their properties and functionality.

• Antibody-Drug Conjugates: 'Magic Bullets' Become Reality

  Cancer therapy has evolved from potent chemotherapy to targeted biological therapy, including antibody-drug conjugates (ADCs). Learn more about ADCs’ makeup, mechanisms, and the development landscape.

• Tracing PS80: How LC‑MS Resolved A Potency Discrepancy

  A targeted LC–MS investigation identifies molecular changes behind potency discrepancies, enabling accurate root‑cause analysis and stronger control of monoclonal antibody product quality.

• Implementing A Disaster Recovery Plan

  When facing a malfunction, having an effective disaster recovery plan can make the difference between a swift fix, and losing your samples and time.

• How Optics And Flow Cytometry Are Improving Pancreatic Cancer Treatment

  The University of Texas researchers are developing an optical system analyzing cancer cell properties to guide treatments, improving patient outcomes and targeting aggressive cancers like pancreatic.

• Proprietary Reactivation Study Demonstrates PFAS Removal And Destruction Expertise

  Thermal reactivation of granular activated carbon is a proven and scalable method to achieve >99.9% destruction removal efficiency for PFAS. This process fully restores the carbon for reuse, providing a sustainable solution that breaks the cycle of "forever chemicals."

• CDMO Uses Robotic Gloveless Isolator For Advanced Therapeutics

  CDMOs must innovate production architectures to meet the demands of advanced therapeutics to ensure a reliable supply and compliance. Discover how these approaches advance modern medicine and improve patient outcomes.

• The City Of Fayetteville's Flood Resiliency In The Face Of Climate Change: Mapping 15 Watersheds

  The city of Fayetteville, North Carolina has always had flooding issues, but it’s been getting worse as weather patterns have been changing. They were hit four years in a row by storms Matthew (2016), Irma (2017), Florence (2018), and Dorian (2019). 

• State Of Open-Source DPI - Challenges, Opportunities And Alternatives

  Learn about open-source Deep Packet Inspection (DPI) technology, its advantages and constraints, and the transition to commercial DPI. Learn about DPI engines and the need for commercial DPI solutions.

• Operational Success By Strategic Investment

  Explore how infrastructure, equipment strategy, and advanced technologies shape a more reliable path for scaling sterile injectable programs.

• Targeted Indication Selection Using Adaptive Design

  What is a Simon 2-stage design, and how was it used to enable each tumor-specific cohort in a Phase 2, multi-cohort oncology trial to be independently assessed for objective response rates?

• Automating The Process Of Filling Media Into Bottles

  Learn how a vaccine manufacturer using a wide range of containers for media and buffer filling was able to increase efficiency by 70% with an automated closed-system solution.