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WHITE PAPERS AND CASE STUDIES

• Targeting Macular Degeneration With Stem Cell Therapy

  A novel stem-cell therapy based upon iPSC-derived RPE cell transplantation was conceptualized as a promising new treatment for AMD and other retinal diseases.

• Advancing Drug Development With Optimized LC-MS/MS Bioanalysis

  Explore the critical role of sample preparation optimization and the application of liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) in bioanalytical method development.

• Leveraging Surface Plasmon Resonance For Characterizing Ternary Complexes

  Uncover how Surface Plasmon Resonance (SPR) can be used to gain real-time, label-free insights into PROTAC binding kinetics and ternary complex formation.

• CDMO Accelerates Contract Manufacturing With Electronic Batch Records

  A prominent CDMO sought a specialized software solution to streamline and accelerate its manufacturing processes, enabling the efficient production of complex, customized products in record time.

• Vial Adapter Transfer Device Compatibility With Cell Therapies

  Needles and syringes are commonly used to retrieve cell therapies from vials, posing the risk of needle stick injury. Explore the suitability of needle-free polycarbonate transfer devices.

• Revolution In The EU Pharmaceutical Legislation Ahead

  Discover the impact revised pharmaceutical legislation will have on the industry by superseding regulations that have fostered the availability of safe and effective medicines for the past two decades.

• Proprietary Reactivation Study Demonstrates PFAS Removal And Destruction Expertise

  Thermal reactivation of granular activated carbon is a proven and scalable method to achieve >99.9% destruction removal efficiency for PFAS. This process fully restores the carbon for reuse, providing a sustainable solution that breaks the cycle of "forever chemicals."

• Collaborative Tech: How Dunea Is Boosting Network Visibility And Resilience

  Integrating high-frequency sensor data with digital twins enhances network visibility and accelerates response times. This collaborative approach allows utilities to detect anomalies instantly, optimize maintenance, and simulate operational scenarios to ensure long-term system resilience.

• No More Swiss Holes: Filling The Gaps In Clinical Trial Disclosure

  This use case shows how sponsors can gain clarity on disclosure requirements when entering a new country.

• Deriving Reliable Clinical Outcome Scores From Continuous DHT Data

  DHT-derived endpoints, especially percentile-based metrics, hold promise for robust, scalable measurement in clinical trials—provided they're chosen statistically and with adherence in mind.

• Performance Of A Customizable DMSO-Free Cryopreservation Media Formulation

  Cryopreservation enables cell therapy by storing cells long-term. A DMSO-free formula preserves cell viability and health, minimizing toxicities linked with traditional cryoprotectants.

• Putting The Squeeze In Sponge Cities: Amsterdam's Waternet And The Innovative RESILIO Blue-Green Roof Project

  The RESILIO project has helped Amsterdam repurpose rooftops as smart blue-green roofs to reuse rainwater and prevent localized flooding. This project, along with other sustainable water initiatives like the Amsterdam Rainproof program, continues to position the Netherlands at the forefront of water management.