High-Volume Scanners

WHITE PAPERS AND CASE STUDIES

• Rapid Startup Phase 1 Cardiomyopathy CRISPR Gene Therapy

  Hereditary transthyretin amyloidosis (ATTRv) is very rare, prompting a Phase 1 trial of in vivo CRISPR/Cas9 gene editing to reduce mutant protein and stop cardiomyopathy progression.

• Converting iPSC To T Cells: Key Challenges And Considerations

  Explore how by addressing challenges in differentiation, clone selection, and manufacturing, iPSC-based T cell therapies could revolutionize cancer treatment and other diseases.

• Full Scale Operations For Parenteral Pharmaceuticals

  Explore how a project team accelerated through milestones in development, approval and execution of Equipment Evaluations, Equipment Specification Documents, Installation Qualification, and Operational Qualifications.

• Suspension Culture Improves iPSC Expansion And Pluripotency Phenotype

  Learn about the advantages of 3D suspension culture for iPSC expansion, including enhanced pluripotency and genetic stability. Discover how this technique yields high-quality iPSCs for regenerative cell therapies.

• FDA Recommendations For Gene Therapy For PMDs

  Explore insight into the strategies and FDA recommendations for executing gene therapy development programs, specifically for primary mitochondrial diseases (PMDs).

• Tackling Product Quality And Safety Issues Through Global Collaboration

  How the development and execution of a tiered support system, and its results, positively impacted this global collaboration on capacity, efficiency, and cost management.

• Cell And Gene Therapy Field Quiet In Q2

  While there weren't any new gene or cell therapy approvals in Q2 2024, the U.S. approved two RNA therapies: Rytelo, an oligonucleotide telomerase inhibitor, and mRESVIA, an mRNA vaccine.

• Regulatory Publishing Expertise Across The Entire Development Journey

  Learn how with expert support, three separate sponsors were able to issue flawless IND, MAA, and NDA submissions to the FDA and EMA, expediting the process of bringing their product to market.

• Lean Six Sigma Methodology Drives Cost Savings: 2 Success Stories

  Unlock significant lab efficiency and financial gains. See how focused optimization of workflows and asset management led to substantial cost savings and reclaimed six-figure value in consumables.

• Achieve Higher Targeted Concentrations

  Single-pass TFF streamlines downstream processing by reducing footprint, shear exposure, and hold-up volumes. Learn how this approach is advancing efficiency across therapeutic and vaccine production.

• Bridging The Gap During Organizational Restructuring For Continuity

  Navigating workforce turnover and restructuring can threaten project timelines. Discover how leveraging an experienced on-site team can ensure long-term continuity.

• Thermo-Acoustic Oscillations In Gas Tubine Engines

  Dr. Sina Kheirkhah's research at the University of British Columbia studies thermo-acoustic oscillations in combustion equipment to prevent damage using high-speed cameras and ultraviolet image intensifiers.