News | July 1, 2020

Lonza Expands Particle Engineering Services

  • Lonza doubles the network jet-milling capacity for supporting development stage projects and expands the capabilities in specialized cGMP handling
  • Lonza adds new dedicated development capacity for spray dry processing

Quote from Christian Dowdeswell, VP Small Molecules Commercial Development, Lonza:
“Particle engineering is a key component of our integrated services across drug substance and drug product development and manufacturing. We see an increasing requirement for phase-appropriate jet milling and spray drying to advance complex molecules and meet more specialized target product profiles across oral and inhaled applications.”

Lonza announced additional investments in its global particle engineering network for expanded capacity and specialized capabilities. Jet milling and spray dry processing for development have been significantly expanded at US and European sites to meet increased demand. Specialized processing capabilities have also been enhanced.

Development capacity (non-GMP assets) has been doubled at the Monteggio (CH) micronization site with investments inclusive of a new glove-box for isolation, upgraded process controls and expanded operator teams. A new micronization development wing has also been brought online at the Quakertown, PA (USA) site. Additionally, a new pharmaceutical spray dryer dedicated to development projects has been added at the Bend, OR (USA) site.

Particle engineering, inclusive of spray dry processing and size reduction through micronization, is a core capability of Lonza. Micronization and spray drying are employed to improve solubility, dissolution rate, bioavailability, processing and flow, as well as controlling particle size distribution for dry powder inhaler (DPI) applications. The trend towards more highly potent molecules, driven primarily by oncology applications, has resulted in the need for expanded contained particle engineering processing.

Lonza has also expanded its specialized processing capability within its particle engineering platform. During the last 12 months, the Monteggio site has revamped its processing assets to allow for 100% segregation of steroids and hormone compounds. Two new cGMP rooms have been designed to reach a proper containment level to meet quality and safety requirements maintaining a high throughput of the micronization processes.

As part of Lonza’s focus on expanded particle engineering services, the external sale of jet milling equipment and containment systems will be curtailed. Going forward, the Monteggio-based engineering and technical team will be entirely focused on supporting the delivery of our micronization services.

More information can be found here at

About Lonza
At Lonza, we combine technological innovation with world class manufacturing and process excellence. Together, these enable our customers to deliver their discoveries in the healthcare, preservation, and protection sectors.

We are a preferred global partner to the pharmaceutical, biotech and specialty ingredients markets. We work to prevent illness and promote a healthier world by enabling our customers to deliver innovative medicines that help treat or even cure a wide range of diseases. We also offer a broad range of microbial control solutions, which help to create and maintain a healthy environment.

Founded in 1897 in the Swiss Alps, Lonza today operates in 120 sites and offices in more than 35 countries. With approximately 15,500 full-time employees, we are built from high-performing teams and of individual employees who make a meaningful difference to our own business, as well as the communities in which we operate. The company generated sales of CHF 5.9 billion in 2019 with a CORE EBITDA of CHF 1.6 billion. For more information, visit

Source: Lonza